Browse All Trials

  • Radiation Therapy With Either Capecitabine or Fluorouracil Before Surgery in Treating Patients With Resectable Rectal Cancer (NSABP-R-04)
  • Treatment of Children With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
  • A Study of Intensity Modulated Radiation Therapy for Pelvic Lymph Nodes and Primary Tumour in Patients with Prostate Cancer
  • Safety Study of the Proteasome Inhibitor PR-171 in Patients With Hematological Malignancies (PX-171)
  • Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis (EU-20619)
  • Paclitaxel and Carboplatin With or Without Celecoxib Before Surgery in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer
  • CPT-11 (Irinotecan), Oxaliplatin and Xeloda (COX) in Patients with Advanced Colorectal Cancer
  • Collecting and Banking Pediatric Brain Tumour Research Specimens
  • Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' Tumour
  • A Phase I/II Study of Concurrent Pemetrexed/Cisplatin/Radiation in Stage IIIA/B Non-Small Cell Lung Cancer
  • Adjunctive Efficacy Study Of The SoftScan® Optical Breast Imaging System
  • Dynamic Breast MRI in Assessing Locally Advanced Breast Cancer
  • A Pilot Study To Evaluate the Effectiveness of Pulsed Time-Domain Optical Spectroscopy for Monitoring the Responses in Neoadjuvant Treatments of Locally-Advanced Breast Cancer
  • Pilot Investigation of Ultrasound Imaging and Spectroscopy and Ultrasound Imaging of Vascular Blood Flow as Early Indicators of Locally-Advanced Breast Cancer Response to Neoadjuvant Treatment
  • Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumours or High-Risk Medulloblastoma
  • Iodine I 131 Metaiodobenzylguanidine and a Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory High-Risk Neuroblastoma
  • Exploring the Role of 3T MRI in Gamma Knife Radiosurgery
  • Randomized Phase III Study of Optimal Sequencing of Hormonal Therapy and Radiation in Patients with T1-T3 Prostate Cancer
  • Does Palliative Chemotherapy Improve Symptoms in Women with Recurrent Ovarian Cancer?
  • Temozolomide and Oral VP-16
  • Clinical Trial of Ridaforolimus Compared to Progestin or Chemotherapy for Advanced Endometrial Carcinoma (8669-007)
  • A Dose Escalation Study of MK1775 in Combination With Either Gemcitabine, Cisplatin, or Carboplatin in Adults With Advanced Solid Tumours (MK-1775-001 AM7)
  • Neuropsychological and Behavioural Testing in Younger Patients With Cancer
  • Online Psychoeducational Intervention Program
  • TEM Prostate
  • Short Neoadjuvant Hemithoracic IMRT for MPM
  • Phase 1 Study Evaluating the Integration of Hypofractional Renal Ablative Radiation Therapy in the Setting of Metastatic Renal Cell Carcinoma
  • The Effects of Chemotherapy on Cognition
  • Does Performing a Confirmatory Tumour Biopsy in Patients with Metastatic Breast Cancer Alter their Management?
  • DCIS Permanent Breast Seed Implant
  • Health Education Materials With or Without a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
  • A Pilot Study of Gentiana lutea (radix), Zingiber officinalis, and Curcuma longa for the Treatment of Anorexia in Cancer Patients
  • Sterotactic Body Radiation Therapy for Unresectable Liver Metastases from Colorectal Cancer
  • Sterotactic Body Radiation Therapy for Unresectable Hepatocellular Cancer
  • Pharmacogenetic Study of Irinotecan Chemotherapy
  • A Phase II Study of Dexamethasone in the Prophylaxis of Radiation-Induced Pain Flare
  • Genetic Analysis in Identifying Late-Occurring Complications in Childhood Cancer Survivors
  • Chemotherapy and Radiation Therapy Compared With Radiation Therapy Alone in Treating Patients With High-Risk Stage I, Stage II, or Stage III Endometrial Cancer
  • Prospective Identification of Risk Factors for Skeletal Related Events in Breast Cancer Patients Receiving Bisphosphonates for Bone Metastases
  • Reform: A Randomised Pilot Study Comparing the Efficacy of 4-weekly versus 12-weekly intravenous Bisphosphonate Therapy in Women with low risk Bone Metastases from Breast Cancer using bone resorption markers
  • Quality of Life in Neoadjuvant Versus Adjuvant Therapy of Esophageal Cancer Treatment Trial
  • Hypofractionated Accelerated Post-Operative Radiation Therapy For Prostate Cancer
  • A comprehensive study of QOL and fatigue in patients with AML (AML QOL Fatigue)
  • Cisplatin, Etoposide, and Two Different Schedules of Radiation Therapy in Treating Patients With Limited Stage Small Cell Lung Cancer
  • Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer That Can Be Removed By Surgery
  • High-Dose-Rate Brachytherapy
  • Biomarkers in Tumour Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
  • Study of Kidney Tumours in Younger Patients
  • Non-invasive Prediction of Microvascular Invasion in Hepatocellular Carcinoma by Blood-Oxygen-Level Dependent Magnetic Resonance Imaging (BOLD MRI)
  • Prostate cancer study of CRT + Upfront ADT vs. PHPC + Salvage ADT
  • Assessment of Cardiotoxicity by Cardiac Magnetic Resonance (CMR) in Breast Cancer Patients Receiving Trastuzumab
  • Irinotecan pharmacogenomics
  • CTC Pros
  • Observational Pilot Study of 18F-Sodium Fluoride (Na18F) Whole Body Positron Emission Tomography (PET) Scans for Imaging Bone
  • Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy
  • A Registry Study of Permanent Breast Seed Implant
  • A Study of MK1775 in Combination With Topotecan/Cisplatin in Patients With Cervical Cancer (1775-008)
  • Contrast-enhanced Ultrasound for Follow-up After Radiofrequency Ablation of Kidney Lesions
  • A Randomized Phase III Study of Standard Treatment +/- Enoxaparin in Small Cell Lung Cancer
  • A Study of R04929097 in Combination With Gemcitabine in Patients With Advanced Solid Tumours
  • Early Diagnosis of Lung Cancer and Mesothelioma in Prior Asbestos Workers
  • Study to Determine the Maximum Tolerated Dose and Evaluate the Efficacy and Safety of CEP-18770 in Patients With Relapsed Multiple Myeloma Refractory to the Most Recent Therapy
  • The Triumph Study
  • Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma
  • Oncology Treatment Decisions
  • Phase 3 Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma
  • Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
  • Osteonecrosis in Children With Acute Lymphoblastic Leukemia
  • An Investigational Drug, Crizotinib (PF-02341066), Is Being Studied In Tumours, Except Non-Small Cell Lung Cancer, That Are Positive For Anaplastic Lymphoma Kinase (ALK)
  • Surgery Versus Radiosurgery for the Treatment of Single Brain Metastases
  • A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies
  • Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumours That Have Been Removed By Surgery
  • The Natural History of Small Renal Masses
  • Conventional Ultrasound for Imaging of Prostate Cancer Extent and Response in Human Cancer Patients
  • Effectiveness of Doxycycline for Treating Pleural Effusions Related to Cancer in an Outpatient Population
  • A Study of MK-1775 in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone for Participants With Platinum-Sensitive Ovarian Tumours With the P53 Gene Mutation (MK-1775-004)
  • The ODYSSEY Study
  • Femoral Bone Metastases
  • The EPIC Study
  • OPTIM DASATINIB
  • Extended Peri-operative Tinzaparin to Improve Disease-free Survival in Patients With Resectable Colorectal Cancer
  • SPY-1
  • A phase I clinical study of BBI608 in adult patient with advanced solid tumours.
  • Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
  • Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL
  • Feasibility of Evaluating Gene Alteration Analysis Using Samples Obtained by EBUS-TBNA in Patients With Lung Cancer
  • ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumours
  • Bone biopsy study
  • Robotic Compared to Fixed Gantry Radiosurgery for Brain Metastases
  • A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella-Zoster Virus (VZV) Vaccine in Adults With HM Receiving Treatment With Anti-CD20 Monoclonal Antibodies (V212-013)
  • Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer
  • Validation of Colon Biomarkers for the Early Detection of Colorectal Adenocarcinoma
  • Prostate Hypoxia FAZA
  • Sentinel Node Biopsy in Endometrial Cancer
  • Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
  • Study of MK-8242 Alone and in Combination With Cytarabine in Participants With Acute Myelogenous Leukemia (P07649)
  • A Study Using 18F-FAZA and PET Scans to Study Hypoxia in Pancreatic Cancer
  • A Phase II Randomized Trial for Early-stage Squamous Cell Carcinoma of the Oropharynx: Radiation Therapy vs Trans-oral Robotic Surgery (ORATOR)
  • A Study of MM-121 With Paclitaxel in Platinum Resistant/ Refractory Advanced Ovarian Cancers
  • Focal Salvage HDR Brachytherapy for the Treatment of Prostate Cancer
  • Outpatient Platelet Transfusions in Myelodysplastic Syndromes and Leukemia: The OPTIMAL Pilot
  • Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
  • Regorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard Therapy
  • Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer
  • Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumours or Leukemia
  • Cancer, fertility and motherhood
  • Nausea and Vomiting in Children Receiving Chemotherapeautic Monotherapy
  • Radical Versus Simple Hysterectomy and Pelvic Node Dissection in Patients With Low-risk Early Stage Cervical Cancer (SHAPE)
  • A Study of Dalotuzumab + MK-2206 and Dalotuzumab + MK-0752 Combination Therapies in Participants With Advanced Cancer (MK-0646-027)
  • Provide Expanded Access to MDV3100 and Monitor Its Safety in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
  • Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumours With Liver Dysfunction
  • Reolysin in Patients With Previously Treated Advanced or Metastatic, Non Small Cell Lung Cancer Receiving Standard Salvage Therapy
  • Thermal Ablation in Larger Liver and Kidney Tumours
  • Pantoprazole and Docetaxel for Men With Metastatic Castration-Resistant Prostate Cancer
  • A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumour
  • A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma
  • Tranexamic Acid Versus Placebo for Blood to Reduce Perioperative Bleeding Post-liver Resection
  • Tumour TARGET Prostate Cancer
  • Dandelion Root Extract in Patients with Refractory Hematologic Malignancies
  • Early Palliative Care for Patients with Advanced Epithelial Ovarian Cancer
  • Stereotactic Radiation Therapy (SBRT) of Lung Metastasis
  • The Prone Breast Radiation Therapy Trial
  • A Study of XL184 (Cabozantinib) in Endometrial Cancer
  • Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Non-small Cell Lung Cancer Pursuing Stereotactic Body Radiation Therapy (SBRT)
  • Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
  • Studying the Physical Function and Quality of Life Before and After Surgery in Patients With Stage I Cervical Cancer
  • A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)
  • Prostate Delineation: High Quality Volume CT
  • The Metformin Active Surveillance Trial (MAST) Study
  • 5 Fraction Stereotactic Body Radiation Therapy for Oligometastases Regimen, for Extra-Cranial Oligometastases
  • Phase I Dose Finding Study for Melatonin in Pediatric Oncology Patients With Relapsed Solid Tumours
  • Dose Escalation Study of CyberKnife® SBRT Boost for Patients With Unresectable Locally Advanced Pancreatic Cancer
  • A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma
  • A Study of MK-1775 in Combination With Cisplatin and Radiation in Cervical Cancer
  • A Study of Cisplatin With or Without MK-1775 in Squamous Cell Cancer of the Head and Neck
  • Cabozantinib S-Malate in Treating Patients With Recurrent or Metastatic Endometrial Cancer
  • Rituxan INF II
  • Overlooked Population at Risk for AIN.
  • Stereotactic Body Radiation Therapy Versus Conventional Radiation Therapy in Medically-Inoperable Non-Small Lung Cancer Patients
  • Study of Trametinib in Advanced Cancer Patients With Hepatic Dysfunction
  • Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules
  • Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer
  • A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer
  • Feasibility Study of Stereotactic Body Radiation Therapy for Early Breast Cancer
  • Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer
  • A Study of CFI-400945 Fumarate in Patients With Advanced Cancer
  • PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery
  • Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile
  • Trial Comparing Nab-Paclitaxel to Paclitaxel in Patients With Advanced Urothelial Cancer Progressing on or After Platinum Containing Regimen.
  • A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer
  • Gadofosveset Trisodium (Ablavar, Gdfos) in Distinguishing Hemangiomas and Metastases: A Prospective Trial
  • Functional Lung Avoidance for Individualized Radiation Therapy (FLAIR): A Randomized, Double-Blind Clinical Trial
  • GTN Therapy on Biomarkers of Immune Escape in Men With Biochemical Recurrence of Prostate Cancer After Primary Therapy
  • "Re-Stimulated" Tumour-Infiltrating Lymphocytes And Low-Dose Interleukin-2 Therapy in Patients With Platinum Resistant High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
  • Prostate Hypoxia - TIC
  • A Study Of PF-05212384 In Combination With Other Anti-Tumour Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)
  • Accuracy of Sentinel Lymph Node Biopsy in Nodal Staging of High Risk Endometrial Cancer
  • Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer
  • Study Using Combined Virtual 4-D Electromagnetic (EM) Tip-Tracked Devices & EBUS in Diagnosis of Lung Nodules
  • Study of Neoadjuvant Vemurafenib for BRAF Mutant Melanoma and Palpable Lymph Node Metastasis
  • Apixaban for the Prevention of Venous Thromboembolism in Cancer Patients
  • Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery
  • MRI Brain Mets Breast (FIESTA)
  • Abdominal Massage for Relief of Small Bowel Obstruction
  • Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
  • Sunitinib or Cediranib for Alveolar Soft Part Sarcoma
  • Prophylactic Antibiotic Regimens in Tumour Surgery (PARITY)
  • Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced Hematological Cancer
  • A Study of Drug Therapies for Salivary Gland Cancers Based on Testing of Genes
  • Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in a Novartis-sponsored Study.
  • A Phase 1b Study of Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast Cancer
  • HAIP-6192
  • Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer
  • Stereotactic Radiation Therapy for Metastatic Kidney Cancer Being Treated With Sunitinib
  • 131I-MIBG Alone VS. 131I-MIBG With Vincristine and Irinotecan VS131I-MIBG With Vorinistat
  • Placebo Controlled Double Blind Crossover Trial of Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma
  • A Safety and Feasibility Study of Mitotane in Prostate Cancer
  • Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction
  • Prostate Screening Study Using MRI in BRCA Carriers
  • Evaluation of SAR408701 in Patients With Advanced Solid Tumours
  • Yoga Fatigue Study
  • Simple Bone Cysts in Kids
  • An Open Label, Single-Centre, Pilot Study of Everolimus With EBRT for the Treatment of mNET Liver Metastasis
  • Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
  • Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma
  • A Study of Trametinib and GSK2141795 Multiple Myeloma
  • Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer
  • A Study of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects With Metastatic Urothelial Cancer and Other Malignant Solid Tumours That Express Nectin-4
  • A Study Comparing AZD-1775 (MK-1775) and Gemcitabine With Gemcitabine Alone in Ovarian, Peritoneal or Fallopian Tube Cancers
  • Correlative Biomarker Study in Patients With Myeloproliferative Disorders
  • Tranexamic Acid During Cystectomy Trial (TACT)
  • Randomized, Open-label, Two-arms, Phase III Comparative Study Assessing the Role of Involved Mediastinal Radiation Therapy After Rituximab Containing Chemotherapy Regimens to Patients With Newly Diagnosed Primary Mediastinal Large B-Cell Lymphoma
  • Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy
  • The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial
  • Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer
  • Stereotactic Image-Guided Neoadjuvant Ablative Radiation Then Lumpectomy
  • Fairly Brief Androgen Suppression and Stereotactic Radiation Therapy for High Risk Prostate Cancer - Protocol 2
  • A Protocol of the Canadian Prospective Study for Hepatocellular Carcinoma Surveillance Using Biomarkers
  • Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas
  • MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine, With Transgenic MAGE-A3 Insertion in Patients With Incurable MAGE-A3-Expressing Solid Tumours
  • Melatonin and Vitamin D in Breast Cancer
  • Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI
  • FAST MRI Study in Breast Cancer Survivors
  • International Rare Histiocytic Disorders Registry (IRHDR)
  • Capturing BRCA1/2 Mutational Status in Women With High Grade Serous Ovarian Cancer and Impact on Clinical Outcome.
  • Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound
  • Cancer Prevention in Women With a BRCA Mutation
  • SF1126 for Patients With Relapsed or Refractory Neuroblastoma
  • Double Blind Placebo Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC
  • N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan
  • Collection of Tissue Samples for Cancer Research
  • Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma
  • A Study of Taselisib + Fulvestrant Versus Placebo + Fulvestrant in Participants With Advanced or Metastatic Breast Cancer Who Have Disease Recurrence or Progression During or After Aromatase Inhibitor Therapy
  • Pharmacokinetic and Safety Study of Lower Doses of Ceritinib Taken With a Low-fat Meal Versus 750 mg of Ceritinib in the Fasted State in Adult Patients With (ALK-positive) Metastatic Non-small Cell Lung Cancer (NSCLC)
  • HBOT Late Radiation Tissue Injury
  • Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-52)
  • Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA
  • Radionecrosis and FDG PET
  • Phase III FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer
  • Cabazitaxel vs Abiraterone or Enzalutamide in Patients With Poor Prognosis Metastatic Castration-resistant Prostate Cancer
  • Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab
  • Comparative Study of Radiation Therapy Treatments to Treat High Risk Prostate Cancer Patients
  • Pharmacological Manipulation of Intrahepatic Arterial Blood Flow in HCC
  • Sentinel Lymph Node Mapping of Oral Cancer Using Near-Infrared Fluorescence Imaging
  • Phase II Copanlisib in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
  • Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
  • Cognitive Intervention After a Brain Tumour
  • Tissue Collection Protocol
  • Prospective Validation of Circulating Tumour Cells & Circulating Endothelial Cells as Biomarkers in Renal Cancer
  • Piloting the Feasibility of FLT-PET/CT Non-Small Cell Lung Cancer Managed With SBRT
  • A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer
  • A Study of Afatinib in Patients With Advanced Cancer With Changes in the HER Gene
  • Towards Optimal Prescription of Chemotherapy in Prostate Cancer
  • Sapanisertib and Osimertinib in Treating Patients With Stage IV EGFR Mutation Positive Non-small Cell Lung Cancer After Progression on a Previous EGFR Tyrosine Kinase Inhibitor
  • Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB or Stage IIIB-IVB Hodgkin Lymphoma
  • Selinexor and Backbone Treatments of Multiple Myeloma Patients
  • Magnetic Resonance-Guided High Intensity Focused Ultrasound for Recurrent Rectal Cancer
  • Olaparib in gBRCA Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapy
  • Computer Training Program for Younger Patients With a Brain Tumour Who Underwent Radiation Therapy
  • Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Favorable-Risk Hodgkin Lymphoma
  • Evaluation of Diet and Exercise in Prostate Cancer Patients
  • A Phase 2b Open-label Study of Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
  • Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia
  • MDS-CAN: A Prospective National MDS Clinical Database and Local Tissue Bank
  • Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma
  • Cone-beam CT Guided Microcoil Localization of Pulmonary Nodules During Video Assisted Thoracic Surgery(VATS)
  • Anti-Androgens and Cabazitaxel in Defining Complete Response in Prostatectomy (ACDC Trial)
  • Early Integration of Palliative Care in Esophageal Cancer Patients
  • Determining the True Incidence of Atrial Fibrillation Before and After Lung Resection
  • Pilot Study of Whole Gland Salvage HDR Prostate Brachytherapy for Locally Recurrent Prostate Cancer
  • Safety and Efficacy of Pomalidomide, Bortezomib and Low-dose Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma
  • KEYS to Succeed: Cognitive and Academic Intervention Program for Children and Adolescents Surviving Cancer
  • Stereotactic Radiation Therapy for Oligometastatic Prostate Cancer
  • A Study of (Interleukin-12) IL-12 in Patients With Acute Myelogenous Leukemia (AML)
  • A Study of Long-Term Responders on Olaparib
  • Nivolumab With or Without Ipilimumab in Treating Patients With Refractory Metastatic Anal Canal Cancer
  • Prospective Comprehensive Molecular Profiling In Neuroendocrine Tumours
  • Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer
  • A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
  • Use of Haploidentical Related Donors for Patients Without Matched Sibling, Unrelated Donor or Cord Blood Units
  • MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma
  • Locally Invasive NSCLC Treated With NEo-Adjuvant Stereotactic Body RadioTherapy and REsection
  • An Investigational Immuno-therapy Safety and Effectiveness Study of Nivolumab in Combination With Brentuximab Vedotin to Treat Non-Hodgkin Lymphomas
  • A Proof of Principle Study of Pembrolizumab With SBRT in TKI mRCC Patients
  • Study to Evaluate 99mTc-MIP-1404 SPECT/CT Imaging in Men With Biopsy Proven Low-Grade Prostate Cancer
  • Study of Palliative Radiation Therapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases
  • Multi-Modality Imaging for Head & Neck Cancer Free Flap Design Assessment
  • Study Comparing Stereotactic Body Radiation Therapy vs Conventional Palliative Radiation Therapy (CRT) for Spinal Metastases
  • An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS
  • A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification
  • Randomized Trial Standard of Care Vascular Access Strategies for (Neo)Adjuvant Trastuzumab-based Breast Cancer Treatment.
  • Nadolol Versus Propranolol in Children With Infantile Hemangiomas
  • Multiparametric MRI for Prostate Cancer Localization and Characterization Using Hyperpolarized Pyruvate (13C) Injection
  • Platelet Transfusion Requirements in Hematopoietic Transplantation
  • Development and Validation of a Health-related Quality of Life Instrument
  • Nivolumab in Eliminating Minimal Residual Disease and Preventing Relapse in Patients With Acute Myeloid Leukemia in Remission After Chemotherapy
  • Evaluation of Afatinib in Maintenance Therapy in Squamous Cell Carcinoma of the Head and Neck (BIBW2992ORL)
  • Personalize my Treatment
  • Robotic Lobectomy vs. Thoracoscopic Lobectomy for Early Stage Lung Cancer
  • Standard of Care Therapy With or Without Stereotactic Radiosurgery and/or Surgery in Treating Patients With Limited Metastatic Breast Cancer
  • A Study of Selicrelumab (RO7009789) in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumours
  • A Study of Oral Ixazomib Maintenance Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation
  • Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer
  • Impact of Positron Emission Tomography (PET) Imaging in Muscle-invasive Urothelial Carcinoma of the Bladder Staging
  • Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study
  • Biopsies in Oncology - Prospective Study of Impact on Patient's Quality of Life.
  • REaCT-vascular Access Her2 Negative Vascular Access Strategies for (Neo) Adjuvant Breast Cancer Treatment Without Trastuzumab
  • An Investigational Immuno-therapy Study of BMS-986205 Given in Combination With Nivolumab and in Combination With Both Nivolumab and Ipilimumab in Cancers That Are Advanced or Have Spread
  • A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC
  • 18F-Fluoroazomycin Arabinoside (18F-FAZA) in Lung Cancer
  • Receiving Radiation Therapy in the MRgRT Research Facility
  • Management of Castration-Resistant Prostate Cancer With Oligometastases
  • Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer
  • Multi-Parametric Assessment of Breast Lymphedema
  • Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC).
  • An Investigational Immuno-therapy Trial of Nivolumab, or Nivolumab Plus Ipilimumab, or Nivolumab Plus Platinum-doublet Chemotherapy, Compared to Platinum Doublet Chemotherapy in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)
  • Brentuximab Vedotin and Gemcitabine Hydrochloride in Treating Younger Patients With Relapsed or Refractory Hodgkin Lymphoma
  • INTense Exercise foR surVivAL Among Men With Metastatic Castrate-Resistant Prostate Cancer
  • The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma
  • Cognitive Sequelae of Adjuvant Endocrine Therapy for the Treatment of Breast Cancer in Older Women
  • Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
  • Lu-DOTATATE Treatment in Patients With 68Ga-DOTATATE Somatostatin Receptor Positive Neuroendocrine Tumours
  • Phase 2 Study of Tucatinib vs Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer
  • Study Comparing Two Different Schedules of Palbociclib Plus Second Line Endocrine Therapy in Women With Estrogen Receptor Positive, HER2 Negative Advanced/Metastatic Breast Cancer
  • Expanded Access Program With Nivolumab Therapy for Treatment of Advanced/Metastatic SqNSCLC or Non-SqNSCLC After One Prior Systemic Regimen
  • Study of Changes and Characteristics of Genes in Patients With Pancreatic Cancer for Better Treatment Selection
  • Study of MEDI4736 (Durvalumab) With or Without Tremelimumab Versus Standard of Care Chemotherapy in Urothelial Cancer
  • Treatment of Canadian Postmenopausal Women With ER+ Advanced Breast Cancer in the Real-World Setting With Hormone Therapy ± Targeted Therapy
  • Stereotactic Radiation Therapy for Oligo-Progressive Non-Small Cell Lung Cancer (STOP-NSCLC)
  • Online MBSR Program for Cancer Survivors With Chronic Neuropathic Pain
  • Myeloproliferative Neoplasms (MPNs) Patient Registry
  • Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of Selicrelumab (RO7009789) With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumours
  • A Study of Cediranib and Olaparib at Disease Worsening in Ovarian Cancer
  • A Study of Venetoclax in Combination With Cobimetinib and Venetoclax in Combination With Idasanutlin in Patients Aged >/= 60 Years With Relapsed or Refractory Acute Myeloid Leukemia Who Are Not Eligible for Cytotoxic Therapy
  • Evaluation of the DCIS Score for Decisions on Radiation Therapy in Patients With Low/Intermediate Risk DCIS
  • A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
  • FAZA PET as Biomarker for Hypoxia in Rectal Cancer
  • Olaparib Maintenance Treatment Versus Placebo in Patients With PSR Ovarian Cancer Who Are in CR or PR to Platinum-based Chemotherapy and Whose Tumours Carry sBRCAm or HRR-associated Genes Mutations
  • A Phase I Study Of Panobinostat/Lenalidomide/Bortezomib/Dex for Relapsed And Relapsed/Refractory Multiple Myeloma (PanRVD)
  • A Study of PEGylated Recombinant Human Hyaluronidase in Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel and Gemcitabine in Participants With Hyaluronan-High Stage IV Previously Untreated Pancreatic Ductal Adenocarcinoma
  • An Investigational Immuno-therapy Study of Nivolumab or Placebo in Patients With Resected Esophageal or Gastroesophageal Junction Cancer
  • An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)
  • Tumour-Infiltrating Lymphocytes and Low-Dose Interleukin-2 Therapy Following Cyclophosphamide and Fludarabine in Patients With Pleural Mesothelioma
  • Selinexor in Advanced Liposarcoma
  • Detection and Localization of Carcinoma Using High Resolution Transrectal Imaging - Proof of Concept Study
  • An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation
  • Assessing the Efficacy and Safety of Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non-Small Cell Lung Cancer Receiving Definitive Chemoradiotherapy
  • A Trial of Trametinib and Panitumumab in RAS/RAF Wild Type Advanced Colorectal Cancer
  • Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy
  • A Phase I Study of CX5461
  • In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma
  • Diffusion Tensor Breast MRI (DTI)
  • The Utility of Circulating Tumour Cells and Plasma microRNA in Esophageal Adenocarcinoma
  • Assessment of New Molecular Imaging Strategies for Prostate Cancer
  • A Phase II, Multicentre Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumours or Relapsed/Refractory Synovial Sarcoma
  • A Randomized Phase III Study of Palliative Radiation of Advanced Central Tumours With Intentional Avoidance of the Esophagus
  • Study of Azacitidine and Durvalumab in Advanced Solid Tumours
  • Schedules of Dexamethasone in Patients Incorrectly Taking Dexamethasone Premedication (REaCT-dexamethasone)
  • Preoperative vs Postoperative IMRT for Extremity/Truncal STS
  • Dabrafenib, Trametinib, and Navitoclax in Treating Patients With BRAF Mutant Melanoma or Solid Tumours That Are Metastatic or Cannot Be Removed by Surgery
  • A Study of Investigational Drug CFI-402257 in Patients With Advanced Solid Tumours
  • An Investigational Immuno-therapy Study to Test Combination Treatments in Patients With Advanced Non-Small Cell Lung Cancer
  • Phase Ib/II Study of INC280 + PDR001 or PDR001 Single Agent in Advanced HCC
  • Controlled Study of Rigosertib Versus Physician's Choice of Treatment in MDS Patients After Failure of an HMA
  • Ponatinib in Participants With Resistant Chronic Phase Chronic Myeloid Leukemia (CP-CML) to Characterize the Efficacy and Safety of a Range of Doses
  • A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
  • MDS Mutations
  • High-Dose Weekly Carfilzomib Plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple Myeloma
  • ADT Exercise Trial and Economic Analysis
  • Pazopanib Paediatric Phase II Trial Children's Oncology Group (COG) in Solid Tumours
  • A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)
  • Development and Evaluation of Rehabilitation Consult for Survivors of Head and Neck Cancer
  • S1011 Standard or Extended Pelvic Lymphadenectomy in Treating Patients Undergoing Surgery for Invasive Bladder Cancer
  • Mindfulness-Based Therapy for Brain Tumour Survivors
  • Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases
  • EUS-FNB vs. Single-incision Needle-knife (SINK) Biopsy for Gastrointestinal SELs
  • Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumours
  • Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer
  • Study of DPX-Survivac Vaccine Therapy and Epacadostat in Patients With Recurrent Ovarian Cancer
  • A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes
  • A Study of the Safety and Tolerability of BMS-986183 in Patients With Liver Cancer
  • MMRF Molecular Profiling Protocol
  • Durvalumab With or Without Tremelimumab in Metastatic Castration Resistant Prostate Cancer
  • Ontario-wide Cancer TArgeted Nucleic Acid Evaluation
  • Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL
  • Phase 1/1b Study to Evaluate the Safety and Tolerability of CPI-444 Alone and in Combination With Atezolizumab in Advanced Cancers
  • Continuing Treatment for Subjects Who Have Participated in a Prior Protocol Investigating Elotuzumab
  • Virtual Peer-to-Peer (VP2P) Support Mentoring for Adolescents With Cancer
  • Granulocyte-colony Stimulating Factors or Antibiotics for Primary Prophylaxis for Febrile Neutropenia
  • A Study to Compare Administration Schedules of G-CSF (Filgrastim) for Primary Prophylaxis of Febrile Neutropenia
  • The NEUROlogically-impaired Extubation Timing Trial
  • MSB0011359C (M7824) in Metastatic or Locally Advanced Solid Tumours
  • Quantitative Ultrasound for the Evaluation of Simple Bone Cyst Healing
  • Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma
  • Quizartinib With Standard of Care Chemotherapy and as Maintenance Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML)
  • A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100)
  • Duration of Anti-PD-1 Therapy in Metastatic Melanoma (STOP-GAP)
  • A Trial of TTI-621 for Patients With Hematologic Malignancies and Selected Solid Tumours
  • Assessment of Response to Pembrolizumab in Metastatic Melanoma: Computed Tomography (CT) Texture Analysis as a Predictive Biomarker
  • An Investigational Immuno-therapy Study to Evaluate the Safety and Effectiveness of Experimental Medication BMS-986207 by Itself and in Combination With Nivolumab in Solid Cancers That Are Advanced or Have Spread
  • Using Virtual Reality to Reduce Procedural Pain in Children With Cancer
  • Testing JNJ-42756493 In Combination With Dexamethasone in Multiple Myeloma That Came Back After a Period of Improvement
  • MRI Versus PSA in Prostate Cancer Screening
  • Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy
  • Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma
  • In the Era of the HPV Vaccine, What Are The Current HPV Subtypes Contributing to High Grade Cervical Dysplasia, Adenocarcinoma in Situ, and Early Cervical Cancer?
  • A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.
  • Durvalumab and Tremelimumab in Patients With Advanced Rare Tumours
  • Focal ExAblate MR-Guided Focused Ultrasound Treatment for Management of Organ-Confined Intermediate Risk Prostate Cancer
  • Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs
  • A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer
  • Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer
  • A Study to Compare Tivozanib Hydrochloride to Sorafenib in Subjects With Refractory Advanced RCC
  • A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)
  • Safety and Efficacy of MAK683 in Adult Patients With Advanced Malignancies
  • A Pilot Study of Genetically Engineered NY-ESO-1 Specific NY-ESO-1ᶜ²⁵⁹T in HLA-A2+ Patients With Synovial Sarcoma
  • Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
  • Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
  • A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumours
  • Hepatocellular Carcinoma Study Comparing Vaccinia Virus Based Immunotherapy Plus Sorafenib vs Sorafenib Alone
  • Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer
  • Impact of 18F-FDG PET-CT Versus Conventional Staging in the Management of Patients Presenting With Clinical Stage III Breast Cancer
  • Clinical Study to Assess the Safety and Adequacy of Effectiveness of the SpectraCure P18 System
  • Cabozantinib S-Malate, Crizotinib, Volitinib, or Sunitinib Malate in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
  • Study to Evaluate Safety, Pharmacokinetics and Therapeutic Activity of RO6874281 as a Combination Therapy in Participants With Unresectable Advanced and/or Metastatic Renal Cell Carcinoma (RCC)
  • Lung-MAP: Nivolumab With or Without Ipilimumab as Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers
  • Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects
  • Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG)
  • Individualised Versus Standard Care for Breast Cancer Patients at High-risk for Chemotherapy-induced Nausea and Vomiting The ILIAD Study
  • A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy
  • Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer
  • Breast Cancer WEight Loss Study (BWEL Study)
  • The Prehabilitation Study: Exercise Before Surgery to Improve Patient Function in People
  • Durvalumab and Tremelimumab ± Platinum-Based Chemotherapy in Patients With Metastatic Squamous or Non-Squamous NSCLC
  • Cervical Ca PROs in Clinical Practice
  • A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma
  • A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line Treatment
  • Oncolytic MG1-MAGEA3 With Ad-MAGEA3 Vaccine in Combination With Pembrolizumab for Non-Small Cell Lung Cancer Patients
  • Dose Optimization Study of Idelalisib in Follicular Lymphoma
  • A Study of the Safety, Tolerability and Effectiveness of Hydroxychloroquine and Itraconazole in Platinum-resistant Epithelial Ovarian Cancer
  • A Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)
  • Palbociclib in Patients With Metastatic Castration-Resistant Prostate Cancer
  • A Phase 1/2 Safety Study of Intratumourally Dosed INT230-6
  • Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer
  • Study of Selinexor and Doxorubicin in Advanced Soft Tissue Sarcomas
  • Cediranib Maleate and Olaparib or Standard Chemotherapy in Treating Patients With Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
  • Immunotherapy And Palliative Radiation Therapy Combined In Patients With Advanced Malignancy
  • Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer
  • Study of Allogeneic Double Negative T Cells (DNT-UHN-1) in Patients With High Risk Acute Myeloid Leukemia
  • An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies
  • Phase II Lung Metcore - Preoperative Metformin for Lung Cancer
  • A Dose Escalation Study of RO7082859 as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
  • Feasibility Study of Using Navigational Bronchoscopy to Perform PDT-Photofrin® in Unresectable Peripheral Lung Cancer
  • A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer
  • Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC
  • HDR Focal: Feasibility Study
  • Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer
  • Study of Niraparib in Recurrent Endometrial Cancer
  • Satisfaction of Patients With Trans-Arterial Radial Access: Quality of Life in Uterine Fibroid Embolization Trial
  • Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative to Placebo Plus Abiraterone Plus Prednisone/Prednisolone in Adult Male Patients With Metastatic Castrate-Resistant Prostate Cancer
  • Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction Cancer
  • Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs. Placebo Plus Chemotherapy for Previously Untreated Locally Recurrent Inoperable or Metastatic Triple Negative Breast Cancer (MK-3475-355/KEYNOTE-355)
  • Study of Pembrolizumab (MK-3475) or Placebo With Chemoradiation in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-412/KEYNOTE-412)
  • A Phase 1 Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumours
  • Study of Lorlatinib (PF-06463922)
  • Assessment of QoL and Outcomes With SBRT for RCC
  • Axillary Reverse Mapping (ARM) Technique
  • Bortezomib, Selinexor, and Dexamethasone in Patients With Multiple Myeloma
  • Incidence of Venous Thromboembolism in Patients Undergoing Major Esophageal Resection
  • Study of Copanlisib in Combination With Standard Immunochemotherapy in Relapsed Indolent Non-Hodgkin's Lymphoma (iNHL)
  • RCT of Olanzapine for Control of CIV in Children Receiving HSCT Conditioning
  • Phase 1b Multi-indication Study of Anetumab Ravtansine in Mesothelin Expressing Advanced Solid Tumours
  • A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-Based Therapy
  • Study of Pembrolizumab (MK-3475) in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057)
  • Pilot Study of Nivolumab in Pediatric Patients With Hypermutant Cancers
  • Follow up to the AVANT Study up to 8 and 10 Years (Median Follow up) in Patients With Colon Carcinoma
  • A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients
  • Hyperpolarized 13C MR Imaging of Lactate in Patients With Locally Advanced Cervical Cancer (LACC) Cervical Cancer
  • An Investigational Immuno-therapy Study of Nivolumab Monotherapy and Nivolumab in Combination With Ipilimumab in Pediatric Patients With High Grade Primary CNS Malignancies
  • A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumour Necrosis Factor (TNF) Inhibitors
  • Trial of Afatinib in Pediatric Tumours
  • Prostate Cancer Subclinical Metastatic Ablative MR-guided Radiation Therapy
  • MAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck Cancers
  • PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Early Breast Cancer
  • PH3 Study of Mirvetuximab Soravtansine vs Investigator's Choice of Chemotherapy in Women With FRa+ Adv. EOC, Primary Peritoneal or Fallopian Tube Cancer
  • MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC
  • A Study of Durvalumab (MEDI4736) and IPH2201 in Solid Tumours
  • A Study to Evaluate Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
  • Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer
  • Alvocidib Biomarker-driven Phase 2 AML Study
  • A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Patients With Advanced Solid Tumours
  • Statins for the Primary Prevention of Heart Failure in Patients Receiving Anthracycline Pilot Study
  • Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS
  • A Study of Atezolizumab Compared With Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or Metastatic Non-Small Cell Lung Cancer Who Are Deemed Unsuitable For Platinum-Containing Therapy
  • Study to Evaluate the Feasibility of 13-C Pyruvate Imaging in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
  • A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)
  • Study of Olaparib (Lynparza™) Versus Enzalutamide or Abiraterone Acetate in Men With Metastatic Castration-Resistant Prostate Cancer (PROfound Study)
  • Safety Study of Anti-LAG-3 in Relapsed or Refractory Hematologic Malignancies
  • Reduction to Preventive Doses of Enoxaparin After 3 to 6 Months of Treatment With Blood Thinners for Cancer-associated Blood Clots
  • A Study Evaluating Venetoclax in Combination With Azacitidine in Subjects With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)
  • Open-Label Extension and Safety Study of Talazoparib
  • Effect of TTFields in Non-small Cell Lung Cancer (NSCLC) Patients With 1-10 Brain Metastases Following Radiosurgery (METIS)
  • Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I
  • Primary Radiation Therapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer
  • Safety Study of Nivolumab to Treat Advanced or Metastatic Non-small Cell Lung Cancer
  • A Study to Investigate Atezolizumab and Chemotherapy Compared With Placebo and Chemotherapy in the Neoadjuvant Setting in Participants With Early Stage Triple Negative Breast Cancer
  • Concurrent Dabrafenib and Trametinib With Sterotactic Radiation in Patients With BRAF Mutation-Positive Malignant Melanoma and Brain Metastases
  • MRG FU With Radiation Therapy for Palliation of H&N Cancer
  • Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)
  • An Open-Label Pharmacokinetics and Safety Study of Talazoparib
  • Detection of Clinically Significant Prostate Cancer With 18F-DCFPyL PET/MR
  • Measurement of Natural Killer Cell Activity in Whole Blood in Men Being Screened for Prostate Cancer With Biopsy
  • Study of Nivolumab in Combination With Ipilimumab or Standard of Care Chemotherapy Compared to the Standard of Care Chemotherapy Alone in Treatment of Patients With Untreated Inoperable or Metastatic Urothelial Cancer
  • Neuroblastoma Precision Trial
  • A Dose Escalation and Combination Immunotherapy Study to Evaluate BMS-986226 Alone or in Combination With Nivolumab or Ipilimumab in Patients With Advanced Solid Tumours
  • Dose Escalation and Expansion Study of GSK525762 in Combination With Fulvestrant in Subjects With Hormone Receptor-positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Advanced or Metastatic Breast Cancer
  • A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma
  • Treatment of Children With Recurrent Refractory Brain/Solid Tumours and Recurrent Ependymoma
  • The Efficacy of the Bladder EpiCheck for Detection of Recurrent Urothelial Cell Carcinoma
  • A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer
  • The ACTIVATE (Adoptive Cell Therapy InVigorated to Augment Tumour Eradication) Trial
  • An Efficacy Study Comparing Oral Ixazomib/Dexamethasone and Oral Pomalidomide/Dexamethasone in Relapsed and/or Refractory Multiple Myeloma
  • Risk Stratified Multidisciplinary Ambulatory Management of Malignant Bowel Obstruction in Gynecological Cancers
  • Epigenetic Reprogramming in Relapse/Refractory AML
  • Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection
  • A Dose-Finding Study of the Second Mitochondrial Activator of Caspases (SMAC) Mimetic Debio 1143 When Given in Combination With Avelumab to Participants With Advanced Solid Malignancies and to Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Platinum-Based Therapy
  • Cognitive-Existential Group Therapy to Reduce Fear of Cancer Recurrence: A RCT Study
  • Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer
  • Dose-Escalation Study of BFCR4350A in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)
  • Avelumab in G2-3 NET
  • Avelumab in G3 NEC
  • A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency
  • A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia Vera
  • Phase I Dose Escalation Study of Topotecan and Pazopanib in Children With Recurrent/Refractory Solid and CNS Tumours (TOPAZ)
  • Expanded Treatment Protocol in Acute Lymphoblastic Leukemia
  • Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumour Status
  • A Study of Rucaparib Versus Physician's Choice of Therapy in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency
  • Perioperative Immunonutrition in Colorectal Cancer Patients Undergoing Abdominal Surgery
  • Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)
  • Central Venous Catheter (CVC) Associated Deep Vein Thrombosis (DVT) in Cancer Patients
  • Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia
  • Pulmonary Rehabilitation Before Lung Cancer Resection
  • Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Unresectable Hepatocellular Carcinoma
  • Feasibility Trial in Men With Hormone Sensitive Oligometastatic Prostate Cancer
  • Study of Pembrolizumab Given With Ipilimumab or Placebo in Participants With Untreated Metastatic Non-small Cell Lung Cancer (MK-3475-598/KEYNOTE-598)
  • IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting
  • Physical Activity for Adolescent and Young Adult Cancer Survivors
  • Exercise for Adults Diagnosed With Rectal Cancer
  • Safety and Efficacy Study of Pembrolizumab (MK-3475) as Monotherapy in the Adjuvant Treatment of Renal Cell Carcinoma Post Nephrectomy (MK-3475-564/KEYNOTE-564)
  • Study to Describe the Management and the Use of Healthcare Resources in Patients With Chronic Lymphocytic Leukemia (CLL) Initiating Venetoclax in Routine Clinical Practice
  • Trial to Assess Safety and Efficacy of Lenvatinib in Combination With Everolimus in Participants With Renal Cell Carcinoma
  • A Study of Subcutaneous Versus (vs.) Intravenous Administration of Daratumumab in Participants With Relapsed or Refractory Multiple Myeloma
  • Sym021 (Anti-PD-1) in Patients With Advanced Solid Tumour Malignancies or Lymphomas
  • An Investigational Immuno-therapy Study to Assess the Safety, Tolerability and Effectiveness of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumours
  • A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma
  • This Study Tests the New Medicine BI 754111 Alone or in Combination With Another New Substance BI 754091 in Patients With Advanced Cancer. The Study Tests Different Doses to Find the Best Dose for Continuous Treatment.
  • A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC
  • Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs
  • A Study to Evaluate the Safety, Pharmacokinetics and Clinical Activity of RO6870810 and Atezolizumab (PD-L1 Antibody) in Participants With Advanced Ovarian Cancer or Triple Negative Breast Cancer
  • Study of Pembrolizumab and Radiation Therapy in Liver Cancer
  • Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia
  • IRX-2 Regimen in Patients With Newly Diagnosed Stage II, III, or IVA Squamous Cell Carcinoma of the Oral Cavity
  • Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients
  • Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
  • Randomized Trial of eOncoNote
  • Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy.
  • An Open-Label, Multi-Centre, Study to Assess the Safety of Fixed-Dose Durvalumab + Tremelimumab Combination Therapy or Durvalumab Monotherapy in Advanced Solid Malignancies.
  • A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia
  • A Window of Opportunity Study to Assess the Modulation of Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) By Preoperative Treatment With BYL719
  • Evaluation of Gd-EOB-DTPA MRI for Detection and Characterization of Liver Nodules in Cirrhotic Patients Undergoing Liver Transplantation and Potential Impact on Transplant Eligibility
  • The Translational Research Image-Guided Operating Room (TRIGORA): Intraoperative 3D Imaging for Head & Neck Surgical Patients
  • Adavosertib, External Beam Radiation Therapy, and Cisplatin in Treating Patients With Cervical, Vaginal, or Uterine Cancer
  • A Study Comparing the Combination of Nivolumab and Ipilimumab Versus Placebo in Participants With Localized Renal Cell Carcinoma
  • A Study Of Daratumumab, Low-Dose Oral Dexamethasone and Cyclophosphamide With Or Without Pomalidomide
  • First-line Esophageal Carcinoma Study With Chemo vs. Chemo Plus Pembrolizumab (MK-3475-590/KEYNOTE-590)
  • Study of Pembrolizumab (MK-3475) in Adults With Recurrent/Metastatic Cutaneous Squamous Cell Carcinoma (cSCC) or Locally Advanced Unresectable cSCC (MK-3475-629/KEYNOTE-629)
  • A Study Looking the Incidence and Severity of Diarrhea in Patients With Early-Stage HER2+ Breast Cancer Treated With Neratinib and Loperamide
  • TAK-659 in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
  • Project: Every Child for Younger Patients With Cancer
  • 18F-FDG PET/MR Imaging for Differentiation of Serous From Non-Serous Pancreatic Cystic Neoplasms: A Pilot Study
  • A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
  • Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML)
  • A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
  • Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)
  • WATChmAN Virtual Testicular Cancer Clinic
  • Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumour and Activation of the MAPK/ERK Pathway.
  • An Investigational Immuno-Therapy Study of Experimental Medication BMS-986277 Given Alone and in Combination With Nivolumab in Epithelial Cancers
  • Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy
  • Cabozantinib and Nivolumab in Treating Patients With Advanced, Recurrent or Metastatic Endometrial Cancer
  • A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer
  • Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell Carcinoma
  • Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer
  • Dinutuximab and Irinotecan Versus Irinotecan to Treat Subjects With Relapsed or Refractory Small Cell Lung Cancer
  • Comparison of Endoscopic Visualization and CT Imaging of Head and Neck Cancers With Pathological Validation Study
  • Prostate Boost Irradiation With Stereotactic Body RT (SBRT)
  • To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.
  • The Link Between Clinical and Physiological Sleep Data and Health-related Outcomes
  • Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumours
  • A Study Evaluating KTE-C19 in Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ZUMA-3)
  • Study Evaluating KTE-C19 in Pediatric and Adolescent Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
  • Exercise in Patients With Glioblastoma
  • A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy
  • Long Term Follow up of Subjects Exposed to Genetically Engineered T Cell Receptors
  • Sexual Health and Rehabilitation eClinic (SHAReClinic)
  • ANET Electrosurgery Applicator Pilot Evaluation Study
  • Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumours and Lymphomas
  • A Safety and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)
  • Liver Regeneration
  • Aspirin in Preventing Recurrence of Cancer in Patients With HER2 Negative Stage II-III Breast Cancer After Chemotherapy, Surgery, and/or Radiation Therapy
  • Study of MK-7162 in Combination With Pembrolizumab (MK-3475) in Adult Participants With Advanced Solid Tumours (MK-7162-002)
  • Rocket® Pleural Catheters: QOL, Feasibility and Satisfaction in Recurrent MPE Patients
  • Phase 2 Study of MLN0128, Combination of MLN0128 With MLN1117, Paclitaxel and Combination of MLN0128 With Paclitaxel in Women With Endometrial Cancer
  • Study of REGN2810 in Adults With Cervical Cancer
  • SUNSET: SBRT for Ultra-central NSCLC- a Safety and Efficacy Trial
  • Trial of Local Consolidation Therapy (LCT) After Osimertinib for Patients With EGFR Mutant Metastatic Non-Small Cell Lung Cancer (NSCLC)
  • Study of Ketamine for Depression in Cancer Patients Receiving Palliative Care
  • Phase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Cutaneous Melanoma
  • Telemedicine Clinic for Prostate Cancer Patients
  • An Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has Spread
  • Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma
  • Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy
  • Study Looking at Biomarkers in Ovarian Cancer
  • Study of Biomarkers in Gynecological Cancers
  • Human Blood Specimen Collection to Evaluate Immune Cell Function
  • MAGE-A4ᶜ¹º³²T for Multi-Tumour
  • PD-1 in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy
  • Maintenance Chemotherapy With or Without Stereotactic Body Radiation Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
  • A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma [IMbrave150]
  • An Investigational Immunotherapy Study of Nivolumab in Combination With Rucaparib, Docetaxel, or Enzalutamide in Metastatic Castration-resistant Prostate Cancer
  • Endoscopic Ultrasound (EUS)-Guided Fine Needle Aspiration (FNA) With Rapid On-site Evaluation (ROSE) of Cytopathology vs. EUS-guided Fine Needle Biopsy (FNB) Alone in the Diagnosis of Pancreatic Solid Lesions
  • PRostate Evaluation for Clinically Important Disease: MRI vs Standard Evaluation Procedures
  • Simultaneous Resection of Colorectal Cancer With Synchronous Liver Metastases
  • Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer
  • A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine/ Oxaliplatin and Bevacizumab
  • NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer
  • A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma
  • A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
  • Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
  • A Superiority Trial to Compare Re-resection of High-grade T1 Bladder Urothelial Carcinoma to no Re-resection for Improving Progression Free Survival
  • Comparing Tapering Low Dose Dexamethasone to Other Standard of Care Therapies for TAPS in Breast Cancer Patients
  • Radium-223 Combined With Dexamethasone as First-line Therapy in Patients With Metastatic Castrate Resistant Prostate Cancer
  • A Safety, PK and Efficacy Study of CC-92480 in Combination With Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma
  • PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiation Therapy for Head and Neck Cancer
  • A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU)
  • A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
  • Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma
  • DPX-Survivac and Checkpoint Inhibitor in DLBCL
  • Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Patients With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation
  • Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)
  • Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer
  • A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma
  • S1316, Surgery or Non-Surgical Management in Treating Patients With Intra-Abdominal Cancer and Bowel Obstruction
  • Giving Information on the Risks and Limitations of Mammography Screening (GIRLS)
  • Critical Care Outcomes of Hematologic Oncology Patients
  • Carfilzomib, Pomalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
  • Multiple Myeloma Molecular Monitoring Study
  • Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumour Malignancies or Lymphomas
  • Sym022 (Anti-LAG-3) in Patients With Advanced Solid Tumour Malignancies or Lymphomas
  • Safety of Continuing CHemotherapy in Overt Left Ventricular Dysfunction Using Antibodies to HER-2
  • Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome
  • Comprehensive Geriatric Assessment and Management for Canadian Elders With Cancer
  • First-in-human Study of ATR Inhibitor BAY1895344 in Patients With Advanced Solid Tumours and Lymphomas
  • A Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Participants With HER2-Positive Early Breast Cancer
  • A Study in Participants Previously Enrolled in a Genentech− and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)
  • The Effectiveness of Online Treatment for Insomnia in Cancer Survivors
  • Combined LDR Boost and HDR Whole Gland
  • A Study of Atezolizumab (Anti−Pd-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck
  • A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases
  • FAZA PET/MRI Sarcoma
  • Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer
  • A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Subjects With Advanced Solid Tumours
  • Prostate Cancer Biomarker Enrichment and Treatment Selection
  • Dose Escalation and Dose Expansion Study of GSK525762 in Combination With Androgen Deprivation Therapy and Other Agents in Subjects With Castrate-resistant Prostate Cancer
  • Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer
  • Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer
  • A Study of Participants With Advanced Prostate Cancer in Canada
  • Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
  • To Assess the Efficacy and Safety of Olaparib Maintenance Monotherapy in the Treatment of Ovarian Cancer
  • Cisplatin Plus Radiation Therapy vs Durvalumab Plus Radiation Therapy Followed by Durvalumab vs Durvalumab Plus Radiation Therapy Followed by Tremelimumab and Durvalumab in Intermediate Risk HPV-Positive Oropharyngeal SCC
  • This Study Aims to Find the Best Dose of BI 907828 in Patients With Different Types of Advanced Cancer (Solid Tumours)
  • Hypofractionated Boost vs Conventionally Fractionated Boost for Localized High Risk Prostate Cancer
  • An Internet Delivered Intervention for Re-Adjustment to Sexual Intimacy With an Ostomy After Colorectal Cancer
  • Vemurafenib in Children With Recurrent/Refractory BRAFV600E-mutant Gliomas
  • Lenvatinib in Combination With Pembrolizumab Versus Treatment of Physician's Choice in Participants With Advanced Endometrial Cancer (MK-3475-775/E7080-G000-309 Per Merck Standard Convention [KEYNOTE-775])
  • Study Comparing Denosumab With Standard Treatment in Urothelial Cancer Patients With Bone Metastases
  • Cannabis Oil for Pain Effectiveness
  • Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies
  • Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer
  • Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy
  • PSMA PET Registry (18F-DCFPyL)
  • Cognitive Support Program for Patients With Brain Metastases
  • Study of AM0010 With FOLFOX Compared to FOLFOX Alone Second-line Tx in Pts With Metastatic Pancreatic Cancer
  • Phase 3 Study of DCC-2618 vs Placebo in Advanced GIST Patients Who Have Been Treated With Prior Anticancer Therapies
  • Liver Transplantation for Early Intrahepatic Cholangiocarcinoma
  • A Study of RO7082859 in Combination With Rituximab or Obinutuzumab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Participants With Non-Hodgkin Lymphomas
  • An Investigational Immuno-therapy Study of Experimental Medication BMS-986178 by Itself or in Combination With Nivolumab and/or Ipilimumab in Patients With Solid Cancers That Are Advanced or Have Spread
  • Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma (KarMMa)
  • Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumours (MK-7123-034)
  • A 3D Analysis of Mandibular Plating Strategies in Oromandibular Reconstruction.
  • A Study of JNJ-63723283, a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, Administered in Combination With Apalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer
  • Study of ASTX727 vs IV Decitabine in MDS and CMML
  • Phase I/II Study of Avelumab in Pediatric Cancer Subjects
  • Lung Cancer Next Generation Sequencing Using the Oncomine Comprehensive Assay
  • Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer
  • A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy
  • Study of the Safety and Efficacy of MIW815 With PDR001 to Patients With Advanced/Metastatic Solid Tumours or Lymphomas
  • The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study
  • Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations
  • SL-401 in Advanced, High Risk Myeloproliferative Neoplasms (Systemic Mastocytosis, Advanced Symptomatic Hypereosinoophic Disorder, Myelofibrosis, Chronic Myelomonocytic Leukemia)
  • A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma
  • Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery
  • A Trial of a Modified Cystoscopy Method to Reduce Pain Perception
  • A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-64619178, an Inhibitor of Protein Arginine Methyltransferase 5 (PRMT5) in Participants With Advanced Cancers
  • Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study
  • Prehabilitation to Improve Cancer Surgery Outcomes
  • WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism
  • A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy
  • Stereotactic Body Radiation Therapy for Breast Cancer
  • Regional Radiation Therapy in Biomarker Low Risk Node Positive Breast Cancer
  • Bevacizumab and Anetumab Ravtansine or Paclitaxel in Treating Participants With Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
  • Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer
  • Stereotactic MRI-Guided Radiation for Localized Prostate Cancer
  • Enabling Symptom Identification and Tracking in Children Receiving Cancer Treatment
  • Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumours (MK-4830-001)
  • A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy
  • Study of BAY1834942 in Patients With Solid Tumours
  • A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumours
  • Incidental Genomics
  • Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059
  • Chemotherapy and/or Metastasectomy in Treating Participants With Metastatic Colorectal Adenocarcinoma With Lung Metastases
  • Safety and Efficacy of LAG525 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.
  • A Study of IMO-2125 in Combination With Ipilimumab Versus Ipilimumab Alone in Subjects With Anti-PD-1 Refractory Melanoma (ILLUMINATE-301)
  • A Study to Investigate the Efficacy and Safety of Two Doses of GSK2857916 in Subjects With Multiple Myeloma Who Have Failed Prior Treatment With an Anti-CD38 Antibody
  • Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma
  • This is a Trial of MG1-E6E7 With Ad-E6E7 and Atezolizumab in Patients With HPV Associated Cancers
  • A Study of Metformin to Improve Tumour Oxygenation in Cervix Cancer
  • Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy
  • A Study of NKTR-214 Combined With Nivolumab vs Nivolumab Alone in Participants With Previously Untreated Inoperable or Metastatic Melanoma
  • Trial of ZW25 in Patients With Advanced HER2-expressing Cancers
  • (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST
  • Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC
  • Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers
  • Observational Study on the Use of Akynzeo® in Patients Receiving HEC
  • Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption for Treatment of Glioma
  • Assessing Impact of CCO's PSO & PC Pathway in Ambulatory HNC Clinics
  • A Study Evaluating the Efficacy of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Subjects With Relapsed/Refractory Diffuse Large B Cell Lymphoma
  • Magnetic Occult Lesion Localization and Imaging (MOLLI)
  • Assessment of Left-sided Cardiac Sparing Through the Use of 3-dimensional Surface Matching-based Deep Inspiration Breath Hold and Active Breathing Control
  • A Phase I/II Study of Betalutin for Treatment of Relapsed Non-Hodgkin Lymphoma
  • PK, PD, Safety, Tolerability of Multiple Dose Regimens of MT-3724 for the Treatment of Patients With Relapsed Non-Hodgkin's B-Cell Lymphoma and B-Cell Chronic Lymphocytic Leukemia
  • Pediatric Longitudinal Cohort Study of Chronic Pancreatitis
  • Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumours
  • Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumour Activity of MSC-1 in Patients With Adv Solid Tumours
  • Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)
  • Move For Surgery - A Novel Preconditioning Program
  • Naxitamab for Neuroblastoma With Osteomedullary Disease
  • An Efficacy and Safety Study of Palovarotene for the Treatment of MO
  • Liquid Biopsy Evaluation and Repository Development at Princess Margaret
  • Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Stage I-III Limited Disease Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation Therapy
  • Outcomes Following Omission of Daily Routine Chest Radiographs Following Pulmonary Resection
  • Palliative Thoracic ImmunoRT
  • Genomic Markers for Measuring Metastatic Risk in Breast Cancer Following Primary Treatment
  • Radiomic Markers for Breast Cancer Metastasis and Treatment Response Using MRI
  • Assessment of Precision Irradiation in Early NSCLC and Interstitial Lung Disease
  • Brentuximab Vedotin and Nivolumab in Treating Participants With Early Stage Classic Hodgkin Lymphoma
  • SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides
  • Non-operative Management for Locally Advanced Rectal Cancer
  • PSMA-PET Registry for Recurrent Prostate Cancer Following Radical Prostatectomy
  • PDR001 in Combination With Platinum-doublet Chemotherapy and Other Immunology Agents in PD-L1 Unselected, Metastatic NSCLC Patients
  • Biofeedback Rehabilitation to Improve Speaking and Eating in Public
  • Efficacy and Safety Study of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in ESA Naïve Subjects Who Require Red Blood Cell Transfusions
  • Smart Phone App for COLOnoscopic PREParation
  • A Study Comparing Obinutuzumab and BGB-3111 Versus Obinutuzumab Alone in Treating R/R Follicular Lymphoma