A Study of LY3435151 in Participants With Solid Tumours

Official Title

A Phase 1a/1b Study of LY3435151 Administered to Patients With Advanced Solid Tumours

Summary:

The reason for this study is to see if the study drug LY3435151 is safe in participants with advanced solid tumours.

Trial Description

Primary Outcome:

  • Number of Participants with LY3435151 Dose-Limiting Toxicities (DLTs)
Secondary Outcome:
  • Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY3435151
  • PK: Cmax of LY3435151 in Combination with Pembrolizumab
  • Overall Response Rate (ORR): Percentage of Participants with Complete Response (CR) or Partial Response (PR)
  • Disease Control Rate (DCR): Percentage of Participants with a Best Overall Response of CR, PR, and Stable Disease
  • Duration of Response (DoR)
  • Time to Response (TTR)
  • Progression Free Survival (PFS)

View this trial on ClinicalTrials.gov

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Resources

Canadian Cancer Society

These resources are provided in partnership with the Canadian Cancer Society

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