5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

Official Title

5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:A Phase II Study (5STAR-PC)


Stereotactic Ablative Body Radiation Therapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, effective and cost effective treatment for high-intermediate and high risk prostate cancer with/without an image-guided intraprostatic boost.

Trial Description

Primary Outcome:

  • Acute Toxicity
  • Acute Toxicity
Secondary Outcome:
  • Quality of Life outcome
  • Biochemical disease-free survival
  • Quality of life outcome
  • Quality of life outcome
  • Economic analysis

View this trial on ClinicalTrials.gov

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Canadian Cancer Society

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